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Accueil > Les équipes > Synthèses Selectives et Organometalliques (SSO) > Thèmes de recherche
Synthesis of Compounds of Synthetic or Pharmaceutical Interest
The team is engaged in the synthesis of several targets of general synthetic interest by applying in-house developed methodologies as key steps. The research of the team in this area, classified by date, is exemplified here below by a concise description of the publications spanning the period 2007-2012.
Stereoselective Synthesis of syn-Β-Amino Propargylic Ethers : Application to the Asymmetric Syntheses of (+)-Β-Conhydrine and (–)-Balanol. The stereoselective synthesis of (...)
New metal-mediated synthetic methods
One of the major current challenges of organometallic chemistry is to establish new processes that meet economic needs and environmental welfare. In this context, the use of organozinc reagents has regained significant interest from the chemical community. Inexpensive and barely non-toxic, their use offers the possibility to develop new reactions that are more efficient and selective and thus reduce the number of synthetic steps to achieve a given transformation. Over the last few years, (...)
(En savoir plus...)New Catalytic Transformations
Catalytic Domino Transformations Domino Transformations allow the generation of several new bonds in a single synthetic operation, starting from simple substrates. The projects of the team deal with the study of original catalytic enchainements generally involving one or more transition metals.
Pd-Catalyzed Domino Carbonylative-Decarboxylative Allylation : an Easy and Selective Monoallylation of Ketones. In the presence of an allyl alcohol, α-chloroacetophenones undergo an (...)
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