Nos tutelles

CNRS

PARTENAIRE DE



Fédération de Chimie FR2769

Rechercher

Accueil > Annuaire > CHEMBIO

WANG Yong
Post-Doc

Sorbonne Université,
4 Place Jussieu, 75252 Paris cedex 5

Couloir 33-43 4ème étage. case 229
Équipe Chembio


Tel:33(0)1 44 27 67 32

courriel:



PhD, Scientific Researcher
IPCM, Chimie ParisTech (ENSCP) and startup FEROSCAN
https://www.researchgate.net/profile/Yong_Wang102
http://www.researcherid.com/rid/K-2762-2014

Research Interests

Bioorganometallic chemistry, organometallic anticancer agents, medicinal chemistry.

Peer-reviewed Publications

Education and Research Experience

  • Sept. 2015-present Feroscan researcher (CDI), Institut Parisien de Chimie Moléculaire (UMR 8232), UPMC.
  • Mar. 2013-June 2015 Postdoctoral researcher of Dr Anne Vessières-Jaouen group, working with Dr Siden Top and Prof. Gérard Jaouen, Laboratoire Charles Friedel (UMR 7223), Chimie ParisTech (ENSCP).
  • July 2011-Mar. 2013 Assistant Professor of Prof. Ya-qiu Long group, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica.
  • 2006-2011 Ph.D. Thesis in Medicinal Chemistry at Prof. Ya-qiu Long group, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica.
  • July-Oct. 2010 Exchange Ph.D. student in Medicinal Chemistry and Chemical Biology at Prof. dr. Robert M.J. Liskamp group, Utrecht Institute for Pharmaceutical Sciences, Utrecht University.
  • 2002-2006 Bachelor of Engineering in Pharmaceutical Engineering, Shandong University.

Peer-reviewed Publications

  1. Y. Wang, F. Heinemann, S. Top, A. Dazzi, C. Policar, L. Henry, F. Lambert, G. Jaouen, M. Salmain, A. Vessières. Ferrocifens labelled with an infrared rhenium tricarbonyl tag : synthesis, antiproliferative activity, quantification and nano IR mapping in cancer cells. Dalton Transactions 2018, 47, 9824-9833.
  2. Y. Wang, P. Dansette, P. Pigeon, S. Top, M. McGlinchey, D. Mansuy, G. Jaouen. A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties. Chemical Science 2018, 9, 70-78. (Inner cover paper)
  3. Pigeon, Pascal ; Wang, Yong ; Top, Siden ; Najlaoui, Feten ; Garcia Alvarez, Maria ; Bignon, Jérôme ; McGlinchey, Michael ; Jaouen, Gerard. A new series of succinimido-ferrociphenols and related heterocyclic species induce strong antiproliferative effects, especially against ovarian cancer cells resistant to cisplatin. J. Med. Chem. 2017, 60, 8358-8368.
  4. Y. Wang, P. Pigeon, M. McGlinchey, S. Top, G. Jaouen. Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups. Journal of Organometallic Chemistry 2017, 829, 108-115.
  5. Yong Wang, Marie-Aude Richard, Siden Top, Patrick M. Dansette, Pascal Pigeon, Anne Vessières, Daniel Mansuy, Gérard Jaouen, Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents : Synthesis, Metabolic Formation from Ferrociphenols and Oxidative Transformation
    Angew. Chem. Int. Ed. 2016, 55, 10431-10434.
  6. Yong Wang, Pascal Pigeon, Siden Top, Michael J. McGlinchey, Gérard Jaouen
    Organometallic Antitumor Compounds : Ferrocifens as Precursors to Quinone Methides.
    Angew. Chem. Int. Ed. 2015, 54, 10230-10233.