PhD, Scientific Researcher
IPCM, Chimie ParisTech (ENSCP) and startup FEROSCAN
https://www.researchgate.net/profile/Yong_Wang102
http://www.researcherid.com/rid/K-2762-2014
Research Interests
Bioorganometallic chemistry, organometallic anticancer agents, medicinal chemistry.
Peer-reviewed Publications
Education and Research Experience- Sept. 2015-present Feroscan researcher (CDI), Institut Parisien de Chimie Moléculaire (UMR 8232), UPMC.
- Mar. 2013-June 2015 Postdoctoral researcher of Dr Anne Vessières-Jaouen group, working with Dr Siden Top and Prof. Gérard Jaouen, Laboratoire Charles Friedel (UMR 7223), Chimie ParisTech (ENSCP).
- July 2011-Mar. 2013 Assistant Professor of Prof. Ya-qiu Long group, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica.
- 2006-2011 Ph.D. Thesis in Medicinal Chemistry at Prof. Ya-qiu Long group, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica.
- July-Oct. 2010 Exchange Ph.D. student in Medicinal Chemistry and Chemical Biology at Prof. dr. Robert M.J. Liskamp group, Utrecht Institute for Pharmaceutical Sciences, Utrecht University.
- 2002-2006 Bachelor of Engineering in Pharmaceutical Engineering, Shandong University.
Peer-reviewed Publications- Y. Wang, F. Heinemann, S. Top, A. Dazzi, C. Policar, L. Henry, F. Lambert, G. Jaouen, M. Salmain, A. Vessières. Ferrocifens labelled with an infrared rhenium tricarbonyl tag : synthesis, antiproliferative activity, quantification and nano IR mapping in cancer cells. Dalton Transactions 2018, 47, 9824-9833.
- Y. Wang, P. Dansette, P. Pigeon, S. Top, M. McGlinchey, D. Mansuy, G. Jaouen. A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties. Chemical Science 2018, 9, 70-78. (Inner cover paper)
- Pigeon, Pascal ; Wang, Yong ; Top, Siden ; Najlaoui, Feten ; Garcia Alvarez, Maria ; Bignon, Jérôme ; McGlinchey, Michael ; Jaouen, Gerard. A new series of succinimido-ferrociphenols and related heterocyclic species induce strong antiproliferative effects, especially against ovarian cancer cells resistant to cisplatin. J. Med. Chem. 2017, 60, 8358-8368.
- Y. Wang, P. Pigeon, M. McGlinchey, S. Top, G. Jaouen. Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups. Journal of Organometallic Chemistry 2017, 829, 108-115.
- Yong Wang, Marie-Aude Richard, Siden Top, Patrick M. Dansette, Pascal Pigeon, Anne Vessières, Daniel Mansuy, Gérard Jaouen, Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents : Synthesis, Metabolic Formation from Ferrociphenols and Oxidative Transformation
Angew. Chem. Int. Ed. 2016, 55, 10431-10434. - Yong Wang, Pascal Pigeon, Siden Top, Michael J. McGlinchey, Gérard Jaouen
Organometallic Antitumor Compounds : Ferrocifens as Precursors to Quinone Methides.
Angew. Chem. Int. Ed. 2015, 54, 10230-10233.
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