The research projects developed in this team are based on mass spectrometry experiments. This technique is a powerful analytical tool which enables detection and quantification of chemicals but it is also a method of choice to study gas phase species.
Two major research axes are thus developed in our team. The first one concerns the analytical aspect of mass spectrometry with methodological development and instrumentation. The second one addresses more fundamental themes as the investigation of reaction mechanisms or the interaction characterization in biological systems.
To perform experiments, we have the following instrumental fleet :
Low resolution mass spectrometers
 ESI/Triple Quadripole Quatro II Waters
(R = 1000) |
 LC ESI/IT Esquire Bruker
(R = 3000) |
 LC ESI/IT LCQ Thermo Scientific
(R = 3000) |
 LC ESI/Q-TOF QStar Applied BioSystems
(R = 10 000) |
High resolution mass spectrometers
 MALDI/TOF autoflex III Bruker
(R = 20000) |
 LC ESI ou DESI/LTQ Orbitrap Thermo Scientific
(R = 100 000) |
 ESI ou nano-ESI/FT-ICR 7T Solarix XR Bruker
(R = 1000000) |
 ESI/FT-ICR 7T Apex Bruker
(R = 1000000) |
Each instrument is characterized by resolution R, sensitivity and a covered mass range.
To contact us
Dr Denis Lesage - Dr Yves Gimbert
Sorbonne Université,
4 Place Jussieu, 75252 Paris cedex 5
Couloir 42-43 4ème étage
Équipe CSOB