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ALVES Sandra
Associate professor

Sorbonne Université,
4 Place Jussieu, 75252 Paris cedex 5

Couloir 42-43 4ème étage
Team CSOB

Tel:33(0)1 44 27 32 64

mail:



Research interests:

Mass Spectrometry applied to organic, inorganic molecules and biomolecules.

Current research:

  • Fundamentals study of gas phase noncovalent interactions
  • Instrumental/Methodological development of mass spectrometry
  • Metabolomics and ultra-high resolution mass spectrometry

Recent results:

Figure 1: Charge Enhancement of Single-Stranded DNA in Negative Electrospray Ionization Using the Supercharging Reagent.

Figure 2: Structural Characterization of Antibody Drug Conjugates in Animal Plasma by High Resolution Mass Spectrometry.

Collaboration Sanofi Aventis

Parcours Scientifique

  • Post-doctoral studies at ETH Zurich (Eidgenössische Technische Hochschule), Switzerland) au laboratoire « Organische Chemie » under the supervision of Pr. Renato Zenobi.
  • Ph. D. thesis under the supervision of Pr. Jean-Claude Tabet
  • Chemistry studies at University of Pierre et Marie Curie

Selected publications:

  1. Analysis of low complex region peptides derived from mollusk shell matrix proteins using CID, high-energy collisional dissociation, and electron transfer dissociation on an LTQ-orbitrap: Implications for peptide to spectrum match. A. Marie, S. Alves, B. Marie, L. Dubost, L. Bédouet, S. Berland. Proteomics, 12 (2012) 1.
  2. Heparin-like glycosaminoglycan/amine salt-bridge interactions: a new potential tool for HLGAGs analysis using mass spectrometry, B. Xue, S. Alves, C. Desbans, M. Souchaud, A. Filali-Ansary, P. Soubayrol, J.-C. Tabet, J. Mass Spectrom., 46 (2011) 689.
  3. Influence of salt bridge interactions on the gas-phase stability of DNA/peptide complexes; S. Alves, A. Woods, A. Delvolve, J.-C. Tabet, Int. J. of Mass Spectrom, 278 (2008) 122.